EFFIPRO® DUO Spot-On Flea & Tick Treatment protects your dog from fleas and ticks, and from perpetuating flea invasions by targeting key developmental steps within the flea life cycle. EFFIPRO® DUO is formulated with a unique drop-lock pipette to ensure precise fingertip control throughout the application. EFFIPRO® DUO contains a combination of PPF (pyriproxyfen) and fipronil, which eliminates fleas and ticks and prevents flea eggs from developing into adult fleas for 12 weeks.